In the section on thermogenic products, we saw that forskohline, the active substance of coleus, through an action mediated by adenylate cyclase and cyclic adenosine monophosphate (cAMP) has the ability to stimulate thyroid activity. Well, by the same mechanism, it activates hormone-sensitive lipases on adipocyte membranes, promoting the emptying of cells from the fat they contain. This supplement, therefore, can also be included in the list of weight-loss products. For the side effects, form and dosage of coleus forskohlii products, see the section on thermogenic supplements.